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any ideas on how to get the activation code for my sony network? can anybody help me. the difference in the mortality rate of copd in patients with as compared with the general population is striking.[@r12] the increasing prevalence of copd in patients with as is probably due to the fact that these patients are also ageing. in this article, the characteristics of patients with copd in the context of as were described. moreover, the analysis of the possible risk factors for exacerbations in patients with as is presented. it was shown that the pulmonary function in patients with as with copd is worse than in copd patients without as. a possible explanation for this fact is the presence of a restrictive ventilatory defect. the most important risk factor for exacerbations was the severity of as, and this was independent of the pulmonary function. also, the severity of as was the main risk factor for hospitalisations and the mortality rate. the severity of as correlates with the exacerbation frequency and the mortality rate. the first two parameters significantly depend on the severity of as, while the last one is not related to the severity of as. the most important risk factor for hospitalisations was the severity of as, and this was independent of the pulmonary function. it was shown that the patients with copd and as are older and have a worse pulmonary function than the patients with copd without as. this was confirmed in this study. there is an increasing prevalence of copd in patients with as, but this is mostly due to the ageing of the population. this could also explain why the mortality in patients with copd and as is higher than in patients with copd without as. there are several strengths and limitations to this study. firstly, the study cohort is relatively large, as it includes patients from a single tertiary centre in eastern europe. secondly, all of the subjects were cross-sectionally assessed. further research, with a prospective longitudinal design, is necessary to assess the impact of this disease on patients' quality of life. conclusion #s5 ========== in the current study, patients with copd and as had worse pulmonary function and greater severity of as than patients with copd without as. the severity of as was also the most important risk factor for exacerbations, hospitalisations and the mortality rate. supplementary material ====================== ###### reviewer comments ###### author's manuscript we thank all of the patients who took part in this study. **contributors:** ls, bp, vk, mr, km, jl, jr and aa contributed to the design of the study. bp, vk, mr, km, jl, jr and aa contributed to the collection and interpretation of data. ls, mr and aa contributed to the statistical analysis. ls, bp, vk, mr, km, jl, jr and aa contributed to the writing of the manuscript. ls, bp, vk, mr, km, jl, jr and aa contributed to the critical revision of the manuscript.